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Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that creates them planning to benefit from naltrexone, compared with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director of the UCLA Addictions Laboratory. The findings are presently available online ( inside journal Neuropsychopharmacology and are published in a upcoming print edition with the journal. Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight loss and the those who go through it you ought to err on the side of caution and allow the FDA do its job and demand some study be done so the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on his or her medications. Researchers discovered that participants taking this drug for a year, lost weight within one month and have kept the weight off throughout the 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of several active ingredient, which may make them more efficient and safer. Combo-pilling may be the newest fad or also the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that by right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise blood pressure level and heart rate, and shouldn't be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high hypertension, and also by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients towards the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. After a patient has admitted inside a rehab centre to the treatment of opiate detoxification, medical practitioner simultaneously start detoxifying the patients body. The patient would feel pain if the treatment starts when he / she are in full senses, so usually an anesthesia injection has been injected with their body and make them fall asleep. 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